MicroRNA-1270 modulates papillary thyroid cancer cell development by regulating SCAI

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

MicroRNA-613 inhibits cell growth, migration and invasion of papillary thyroid carcinoma by regulating SphK2

MicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in carcinogenesis. In this study, we investigated the biological function and mechanism of miR-613 in the regulation of papillary thyroid cancer (PTC) development. We found that miR-613 was downregulated in PTC cell lines and tissues, and overexpression of miR-613 significantly suppressed PTC cell gro...

متن کامل

MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1

miR-146a is a NF-κB induced microRNA that serves as a feedback regulator of this critical pathway. In mice, deficiency of miR-146a results in hematolymphoid cancer at advanced ages as a consequence of constitutive NF-κB activity. In this study, we queried whether the deficiency of miR-146a contributes to B-cell oncogenesis. Combining miR-146a deficiency with transgenic expression of c-Myc led t...

متن کامل

BRAF-Activated Long Noncoding RNA Modulates Papillary Thyroid Carcinoma Cell Proliferation through Regulating Thyroid Stimulating Hormone Receptor

PURPOSE The importance of long noncoding RNAs (lncRNAs) in tumorigenesis has recently been demonstrated. However, the role of lncRNAs in development of thyroid cancer remains largely unknown. MATERIALS AND METHODS Using quantitative reverse transcription polymerase chain reaction, expression of three lncRNAs, including BRAF-activated long noncoding RNA (BANCR), papillary thyroid cancer suscep...

متن کامل

Association between microRNA polymorphisms and papillary thyroid cancer susceptibility.

OBJECTIVES Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer, which accounts for 80-90% of all thyroid cancer cases. Though the pathological mechanism hasn't been fully understood, it is reported that both environmental and genetic factor may contribute to the PTC susceptibility. MicroRNAs (miRNAs) are small non-coding RNA molecules which function as the suppressors to...

متن کامل

Cytotoxicity Effect of Extract of Hull Less Seed Pumpkin on Human Papillary Thyroid Cancer Cell Line

Introduction: Thyroid cancer is the most common endocrine malignancy tumor, and its incidence is increasing. Chemotherapy drugs such as Paclitaxel (PTX) are common treatment for cancer, but they have many side effects. Plants are as a source of anticancer agents.  The purpose of this study was the assessment of cytotoxic effects of hydro-alcoholic extract in comparison with those of Paclitaxel ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biomedicine & Pharmacotherapy

سال: 2019

ISSN: 0753-3322

DOI: 10.1016/j.biopha.2018.08.150